To explore the role of dynamin in the early phase of preAC establishment, we needed a tool that can efficiently shut off the dynamin function at the time of initial membranous organelle reorganization (i.e., at 4 hpi) and would not interfere with earlier events in the course of MCMV infection (i.e., establishment of infection, expression of MCMV early-gene function). This evidence concerns the gene DNM1 and infection.