To examine whether the induction of EMT reduces HER2 expression, we analyzed mRNA expression of ERBB2, epithelial phenotype markers CDH1, EPCAM, MUC1 and OCLN, mesenchymal phenotype markers CDH2, FN1, SNAI2, and VIM in the A549 cell line (HER2-high human lung cancer epithelial cell line). Here, SNAI2 is linked to lung cancer.