For this, we studied the interactions of ERBB2 chromatin with its upstream and downstream chromatins in HCC-1954 and MCF7 breast cancer cell lines by analyzing the experimental IM-PET (Integrated Methods for Predicting Enhancer Targets) and ChIA-PET (Chromatin Interaction Analysis by Paired-End Tag Sequencing) data from the cell lines available at 4Dgenome database [23]. Here, ERBB2 is linked to breast carcinoma.