TG and hyperthyroidism: Subclinical hypothyroidism, defined as a normal FT4 and moderately elevated TSH levels, affects approximately 5% of women and 3% of men in the United States, and 0.5% of the adult population may be suffering from undiagnosed overt hypo- or hyperthyroidism, characterized by low or high levels of thyroid hormones, respectively [37,38,39,40].