Whole-genome sequencing (WGS) of paired samples showed that the genomic structure of SMM is similar to symptomatic MM, and typical MM driver events are observed already at the SMM stage, i.e., t(4; 14), t(11; 14), del(1p), amp(1q21), or mutations in the NRAS and DIS3 genes [61]. The gene discussed is NRAS; the disease is Miyoshi myopathy.