In addition, thirteen differential cytokines, among them eleven increased in ALS and two in OND, were observed (IL-6, GM-CSF, IL-2, IL-15, IL-17, CCL4, FGF basic, G-CSF, VEGF, CCL3, CCL2; IL-10, IFN-y). This evidence concerns the gene CSF2 and amyotrophic lateral sclerosis.