In fact, though the ELANE mutation alone, unreported in the GnomAD database thus far, can explain the cyclic neutropenia of this patient, we cannot exclude that TNFRSF13B, present with a variant showing no homozygotes in the same database, may also be involved in the clinical phenotype [38]. The gene discussed is TNFRSF13B; the disease is Decreased total neutrophil count.