TNFRSF13B and autoimmune lymphoproliferative syndrome: Indeed, among these latter cases, the TNFRSF13B p.Glu117Glyfs*35 variant, though predicted to be of an unknown significance, found in the ID100 patient (see Table 2 and next paragraph) might account for, either alone or with the heterozygous AIRE p.Glu517Ter variant (Table 1), her ALPS-like phenotype.