TARDBP and amyotrophic lateral sclerosis: Our efforts focused on typical neurodegenerative disease-associated CSF biomarkers (TDP-43, Aβ42, τP-181 and τT) and on genes that either have as their protein product the above biomarkers (TARDBP, APP, MAPT) or are commonly associated with FTD/ALS (C9orf72).