Five bioflavonoids obtained from moss fern (Selaginella doederleinii) were observed to inhibit non-small cell lung cancer cells by suppressing XIAP and survivin expression, increasing the upregulation of caspase-3/cleaved-caspase-3, inducing cell apoptosis in A549 cells with low toxicity to non-cancer cells MRC-5 cells [186]. The gene discussed is CASP3; the disease is non-small cell lung carcinoma.