Zuo and colleagues also showed that ischemia preconditioning (IPC) in a model of 10-min global cerebral ischemia increased neuronal resistance from cerebral ischemia via no change in Drp1 expression in the CA1 hippocampus, increased translocation of Drp1 in the CA3 hippocampus, and increased COX4 and LC3 expression. The gene discussed is DNM1L; the disease is brain ischemia.