A recent study on ADLPAPT mice (carry amyloid precursor protein (APP), tau, and presenilin-1, with six mutations) disclosed that daily transfer of fecal microbiota alleviated a myriad of AD-related pathological signs and features, including gliosis, Aβ accumulation, tau-pathology, and MCI. The gene discussed is MAPT; the disease is Alzheimer disease.