BME treatment of Cal27 and JHU022 oral cancer cell lines downregulated the protein and mRNA expression levels of glycolytic genes phosphofructo kinase (platelet) (PFKB), pyruvate kinase muscle (PKM), pyruvate dehydrogenase kinase 3 (PDK3), glucose transporter-1 (SLC2A1/GLUT-1) and lactate dehydrogenase alpha (LDHA). The gene discussed is SLC2A1; the disease is lip and oral cavity carcinoma.