CYP11B1 and adenoma: For other steroidogenesis related enzymes, such as 3β-Hydroxysteroid dehydrogenase (HSD3B), 17α-hydroxylase (CYP17A1), and 11β-hydroxylase (CYP11B1), their IHC staining was not enhanced in the adenoma, but was observed in the adjacent adrenal gland tissues.