In PCa, seven ALDH genes (ALDH1A1, ALDH1A3, ALDH3A1, ALDH4A1, ALDH7A1, ALDH9A1, and ALDH18A1) are found elevated over healthy prostate tissues and potentially contribute to the ALDH activity measured by ALDEFLUOR assay. The gene discussed is ALDH1A1; the disease is posterior cortical atrophy.