ALDH2 and neoplasm: In another comparative study, Stevenson et al. showed that ALDH1A1, ALDH2, and ALDH9A1 proteins are present in lymph node metastasis specimens of breast cancer, pancreatic ductal adenocarcinoma, and prostate cancer, indicating a potential common role of these proteins in the development of lymph node metastases in patients with different tumor entities [163].