With the help of the Ingenuity Pathway Analysis Database, BIOGRID 3.4, and STRING 10 databases, Nim et al. derived a signature of two genes to distinguish for shorter and longer disease-free survival in PCa patients: cytochrome P450 26A1 (CYP26A1) and retinol dehydrogenase 10 (RDH10). Here, RDH10 is linked to posterior cortical atrophy.