CXCL8 and ovarian cancer: However, the study showed a correlation between higher serum IL-8 level and the ratio of neutrophils to lymphocytes ≥ 4, the ratio of thrombocytes to lymphocytes ≥ 200 and altered level of CA125, and the FIGO IIIC stage of disease, which puts IL-8 as a marker of poor prognosis in ovarian cancer [27].