Although SAHA inhibited migration and proliferation of all analyzed BC cells in a time- and dose-dependent fashion, MDA-MB-468 cells with a more mesenchymal phenotype were found to overexpress mesenchymal markers (e.g., N-cadherin), whereas epithelial phenotype BC cells (T47D, MCF7) responded to SAHA treatment by an increase of epithelial markers (e.g., E-cadherin) expression. This evidence concerns the gene CDH1 and breast cancer.