The results showed that HOMA-IR (odds ratio (OR) = 0.126, p < 0.001), PSA serum levels (OR = 0.539, p < 0.001), HDL cholesterol (OR = 0.040 p < 0.001) and lower sTWEAK serum levels (OR = 1.002 p < 0.001) were independently associated with the presence of PCa (Figure 1C). The gene discussed is KLK3; the disease is posterior cortical atrophy.