HMGB1 and prostate adenocarcinoma: After differential gene expression analysis between the two groups, we found 31 and 79 genes (in prostate adenocarcinoma and ovary cystadenocarcinoma, respectively) encoding HMGB1-interacting proteins, which were more highly expressed in the HMGB1-high group with statistical significance according to the cBioportal analysis record (Figure 5B).