In contrast to the data presented above, MNT can also act as an oncogene cooperating with Myc as: (a) T-cell-specific homozygous Mnt deletion prevented thymic lymphoma development in mice overexpressing the Myc protein in T cells; (b) Mnt heterozygosity slowed Myc-driven tumorigenesis; (c) Mnt deletion in homozygosis impairs lymphomagenesis in Eμ-Myc mice. Here, MNT is linked to thymus lymphoma.