According to RNA sequencing results, in addition to cholinergic-related genes, BPDCN cases, compared to normal pDCs, overexpressed many genes usually contributing to the survival, development and function of the nervous system (e.g., gene coding for nerve growth factors, GABA receptors, and neurotrophic tyrosine kinase receptors) (Table S7). The gene discussed is NGF; the disease is CD4+/CD56+ hematodermic neoplasm.