For example, YAP activation is associated with TAM recruitment and M2 phenotype polarization, leading to a pro-tumorigenic or immune suppressive environment, potentially via C-C motif chemokine ligand 2 (CCL2 or MCP1) activation, as shown in hepatocellular carcinoma [138,139,140]. The gene discussed is CCL2; the disease is hepatocellular carcinoma.