To investigate whether NRIP1 circRNA (circNRIP1; chr21:15,043,574-15,014,344, Figure 2a) could be employed as a potential biomarker for NSCLC, we analyzed the expression by RT-qPCR (criterion #4) in an independent cohort of platelet samples collected from 23 NSCLC patients and 24 asymptomatic individuals (Table 2, Supplementary Figure S4a). Here, NRIP1 is linked to non-small cell lung carcinoma.