Ectopic expression of CRIPTO1 (an oncofetal, membrane-associated protein of the epidermal growth factor (EGF) cryptic family 1 gene (CFC) family) upregulated ZEB1 and activated the SRC pathway via microRNA-205 (miR-205) downregulation, thereby promoting EMT and erlotinib-resistance in EGFR-mutant NSCLC cell lines [37]. Here, ZEB1 is linked to non-small cell lung carcinoma.