This benefit seemed to be independent of the histological subtype (AC: HR 0.75, 95% CI 0.59–0.96; SCC: HR 0.61, 95% CI 0.42–0.88) and PD-L1 expression (tumor-cell PD-L1 expression ≥1%: HR 0.75, 95% CI 0.45–1.24; <1%: HR 0.73, 95% CI 0.57–0.92; indeterminate or not evaluated: HR 0.54, 95% CI 0.27–1.05). The gene discussed is CD274; the disease is neoplasm.