Analysis of the CRC patient dataset revealed that the expression of OLFML3 mRNA significantly correlated with the expression of mRNA encoding molecules specific for activated immune and inflammatory cells, immune checkpoint inhibitors PD-L1, PD-1, and CTLA4, and with the expression of HAVCR2, a molecule expressed by activated IFN-γ-producing immune cells (Figure 6F,G and Figure S8C,D). Here, CTLA4 is linked to colorectal carcinoma.