PDPN and neoplasm: To assess the effect of rec46A9 and rec9F8 on MC38 tumor vascularization, we performed Pecam1 IHC staining (Figure 3C) and determined the frequency of vascular and lymphatic endothelial cells in tumor cells suspensions using CD45/Pecam1/Pdpn staining of endothelial cells by flow cytometry (Figure 3D).