CXCR2 and neoplasm: The same group, applying a similar experimental microfluidic approach, found that MDA-MB-231 extravasation was mediated by C-X-C Motif Chemokine Receptor 2 (CXCR2) in tumour cells and the chemokine CXCL5 secreted by the bone mimicking environment, as CXCR2 blocking decreased extravasation [262].