DDIT3 and diffuse large B-cell lymphoma: One of these studies included next generation sequencing (NGS) data obtained from the group of Feng, who first reported that among 678 identified exosomal miRNAs, 37 exosomal miRNAs were found to be upregulated and 17 exosomal miRNAs were significantly downregulated in R-CHOP-resistant DLBCL cells when compared to parental DLBCL cells.