USP44 and prostate adenocarcinoma: Furthermore, we observed a negative association between USP44 mRNA expression and the average methylation value of cg23982858, cg009275554, cg22538054, and cg03308628 probes in TCGA-PRAD tumors (Firehose Legacy)(Pearson r = −0.5905, p < 0.0001; Figure 2B).