In fact, a robust set of main BCP markers (CD34, CD19, CD10, CD20, plus CD38 and CD45) constitutes the backbone of the 8-color B-ALL MRD tubes proposed by main clinical studies, showing significant concordance between MFC and RQ-PCR approaches for B-ALL MRD monitoring [50]. The gene discussed is PTPRC; the disease is acute lymphoblastic leukemia.