Functional studies revealed that BCL2A1 enhanced foci formation ability in serum starvation medium, anoikis resistance, tumor colony formation capacity in soft agar, ex vivo cultured mouse omenta, and in vivo tumor dissemination, implying that BCL2A1 was involved in cell survival and other oncogenic properties of ovarian cancer cells, especially under stress conditions. The gene discussed is BCL2A1; the disease is ovarian cancer.