Somatic mutations of ATM and ATR were associated with higher HRD in BLCA, LUAD, CRC, PRAD, head–neck squamous cell carcinoma (HNSC), BRCA, and kidney renal clear cell carcinoma (KIRC) (FDR < 0.008, Table 1). The gene discussed is ATM; the disease is head and neck squamous cell carcinoma.