AGTR2 and central nervous system cancer: For instance, according to transcriptional network analysis, the positive expression of Angiotensin II Receptor Type 1 (AGTR1) and Angiotensin II Receptor Type 2 (AGTR2) have been correlated with different sets of hub genes involved in protumoral function in the C6 glioma cell line, suggesting that both Angiotensin II (Ang II) receptors may represent potential therapeutical targets [8,9].