Three panels of partially overlapping miRNAs were deregulated in HCC versus CHC patients (miR-602, miR-122, miR-181b, miR-125a-5p downregulation, and miR-192 upregulation), in HCC versus the LC group (miR-199a-3p, miR-192, miR-122, miR-181b, miR-224, miR-125a-5p, miR-885-5p upregulation, and miR-22 downregulation), and in CD133+ cells from the HCC group compared to CHC and LC patients (miR-192, miR-122, miR-181b and miR-125a-5p upregulation). Here, PROM1 is linked to laryngotracheoesophageal cleft.