ELOVL2 and breast cancer: Analyses in a spheroid-induced epithelial-mesenchymal transition (EMT) model demonstrated a dramatic reduction in the ratio of C22:6n3 (docosahexaenoic acid, DHA) to C22:5n3 in spheroid cells, similarly to the down-regulation of ELOVL2, a process associated with the induction of metastatic characteristics in BC cells.