The effect of tissue type was similar between IDH-wildtype glioblastoma patients, where the elasticity was comparable between tumor and peritumoral white matter (ratio = 0.89, 95% CI 0.57–1.39, p = 0.593), and the average of IDH-wildtype WHO grade II and III astrocytoma cases. Here, IDH2 is linked to astrocytoma (excluding glioblastoma).