RUNX1 and acute myeloid leukemia: Since 2006, molecular studies (fusion genes AML1-ETO, PML-RARA, CBFβ-MYH11, MLL-AF4, MLL-AF9, and MLL-ENL, as well as FLT3-ITD and WT1 overexpression) have been performed in the central laboratory in Krakow as the standard diagnostic procedure in all pediatric patients with AML.