The RTK subgroups G1/EGFR, G2/FGFR3, G5/PDGFRA, and G6/Multi-RTK accounted for roughly two-thirds of the glioblastoma IDH-wild-type cases, indicating a major role of RTKs in the pathogenesis of glioblastoma. The gene discussed is FGFR3; the disease is glioblastoma.