BAX and gastric cancer: Andrographolide, a labdane diterpenoid from the herb Andrographis paniculata Nees Herba (Acanthaceae), inhibits proliferation and metastasis of gastric cancer SGC-7901 via cell cycle arrest; upregulation of Bax, Bik, and TIMP-1/2; and downregulation of Bcl-2, CD147, MMP-2, and MMP-9 [106].