Nuclear factor kappa-B (NF-κB), c-Jun N-terminal kinase (JNK), and signal transducer activator of transcription 3 (STAT3), inflammatory cytokines, tumor necrosis factor (TNF), interleukin (IL)-1/6, tumor-derived cytokines such as fasciclin (Fas) ligand, and vascular endothelial growth factor (VEGF) are major targets of regulation for the prevention and treatment of gastric cancer [14,15,16,17,18]. The gene discussed is FAS; the disease is gastric cancer.