These genes are responsible for many important cellular processes (e.g., proliferation and apoptosis) and are associated with the pathogenesis of DLBCL, BCL2, RUNX2, NOTCH2, MYC, APC, BMPR2, PTEN, IL6, CAMTA1, and PRKAR1A among them. The gene discussed is NOTCH2; the disease is diffuse large B-cell lymphoma.