In another RNA-seq dataset generated from 116 early-onset prostate cancers (diagnosis ≤ 55 years) [24], a significant increase of PAQR6 gene expression was found in late-stage (pT3b-pT4) patients compared to early-stage (pT2a/b) patients (Figure 5C). The gene discussed is PAQR6; the disease is prostate carcinoma.