IRF5 and systemic lupus erythematosus: Finally, a genome-wide association (GWA) study in Koreans revealed 10 risk regions—STAT1-STAT4, TNFSF4, TNFAIP3, IKZF1, HIP1, IRF5, BLK, WDFY4, ETS1, and IRAK1-MECP2—to be implicated in SLE [50].