VIM and breast cancer: As it regards the present issue, curcumin has shown the ability to (i) inhibit proliferation and colony formation of breast cancer cell lines, MCF-7 and MDA-MB-231; (ii) suppress the migration and invasion of MDA-MB-231 cells; (iii) downregulate the mRNA expression of vimentin, fibronectin, and β-catenin; (iv) upregulate the mRNA expression of E-cadherin.