In agreement with this suggestion, another study carried out on individuals diagnosed with NAFLD indicated that DNA methylation at specific CpGs within Pparα, Pparγ, TGFβ1, Collagen 1A1, and PDGFα genes can distinguish mild from severe NAFLD-associated fibrosis [83]. This evidence concerns the gene TGFB1 and metabolic dysfunction-associated steatotic liver disease.