When compared to HC, monocytes from acute COVID-19 patients had higher size (FSC) and granularity (SSC), higher expression of CD11b, CD16 and CD33, similar expression of CCR2, CCR5 and CD86, and a marked downregulation of HLA-DR, as previously reported [12,15,24] (Figure 1C). Here, ITGAM is linked to COVID-19.