Furthermore, reanalysis of the GSE40272 PCa cohort data (n = 98) showed that patients with high psa/klk3 expression had an elevated prognostic index, and were at significantly higher risk of biochemical recurrence (BCR), compared to the low expressors (2.01-fold, p = 7.76 × 10−24) (Figure 3E). Here, KLK3 is linked to posterior cortical atrophy.