CD5L and posterior cortical atrophy: Of therapeutic relevance, we also found that compared to patients who were not respondent to Pembro from our in-house PCa cohort, the Pembro_responders exhibited significantly higher levels of AIM/CD5L and PDL1 proteins expression, while conversely, PSA/KLK3 protein expression was higher in the Pembro_non-responders (Figure 7G).