The inactive WAVE2 forms a complex with the IQ motif containing GTPase activation protein 1(IQGAP1) and kinesin family member 5B (KIF5B), which is a component of a motor protein complex that regulates and mediates the transport of cytoplasmic granules and molecules of RNA in migrating breast cancer cells [84]. The gene discussed is IQGAP1; the disease is breast cancer.