In a study of Parkinson’s Disease, miR-182-5p and miR-183-5p were shown to mediate neuroprotection of dopaminergic (DA) neurons in vitro and in vivo by down-regulating the expression of FOXO3 and FOXO1 and enhancing PI3K-Akt signaling [68]. Here, FOXO3 is linked to Parkinson disease.