Interestingly, in contrast to ICU patients without active malignancy, ICU patients with active malignant disease had higher serum PLIN2 concentrations (2.45 (0.48–40) μg/dL vs. 5.02 (1.78–48.3) μg/dL, p = 0.007; Figure 2G). Here, PLIN2 is linked to cancer.