In addition, there was a significant main effect of the subgroup factor on the log10-transformed concentrations of ATX (F(2,130) = 8.314, p < 0.001), and the post hoc test showed significantly higher ATX concentrations in the liver disease subgroup than in the non-liver disease subgroup (p < 0.05) and the control group (p < 0.01) (Figure 1D). Here, ENPP2 is linked to liver disorder.