BDNF and pancreas disorder: Indeed, we have observed that alcohol-induced liver and pancreas diseases are associated with elevated concentrations of interleukin (IL)-8 [35] and IL-6 [36], and decreased concentrations of IL-17A [36] and growth factor brain-derived neurotrophic factor (BDNF) [2], which suggests a potential role of these molecules as indicators or biomarkers of these comorbid diseases in accessory gastrointestinal organs.