Central neuroinflammation in conjunction with angiogenesis, i.e., increased blood vessel densities and vascular endothelial growth factor (VEGF) expression in the spinal cord, has been shown in human multiple sclerosis and rodent models of experimental autoimmune encephalomyelitis (EAE) and seizure [19,20,21,22]. Here, VEGFA is linked to experimental autoimmune encephalomyelitis.