The siRNA-mediated knockdown of GLI1 could also abolish Gal-1-induced gastric cancer invasion and expression of mesenchymal markers, including N-cadherin, vimentin, and SNAI1, and invasion-related protein MMP9, as well as restore the expression of the epithelial marker, E-cadherin [119]. The gene discussed is GLI1; the disease is gastric cancer.