Evidently, p70S6K2 inhibited GSK3β function by phosphorylating its Ser9 residue, which in turn stabilized GLI1 protein levels and enhanced cell viability/proliferation of non-small cell lung cancer cell lines, and this effect can be reversed upon p70S6K2 silencing. The gene discussed is RPS6KB2; the disease is non-small cell lung carcinoma.