GLI proteins, especially GLI1, have demonstrated prognostic values for predicting survival among diverse cancer types, including breast cancer [204,205,206,207,208], liver cancer [208,209], pancreatic cancer [208,210], ovarian cancer [208,211,212,213], glioma [214], prostate cancer [215], colon/colorectal cancer [81,216,217] gastric cancer [218,219,220], AML [208], and medulloblastoma [221]. This evidence concerns the gene GLI1 and Familial prostate cancer.