Interestingly, Gal-1 was found to induce vasculogenic mimicry (VM), an endothelial-independent vascular system that allows blood transportation, through GLI1-mediated upregulation of VM-related molecules, including MMP2, MMP14, and laminin5γ2, in gastric cancer cell lines and tumor xenografts [120]. This evidence concerns the gene LGALS1 and neoplasm.